Developmental Gene Expression Differences between Humans and Mammalian Models
نویسندگان
چکیده
منابع مشابه
Segmental duplications contribute to gene expression differences between humans and chimpanzees.
In addition to specific changes in cis- and trans-regulatory elements, structural changes in the genome are hypothesized to underlie a large number of differences in gene expression between species. Accordingly, we show that species-specific segmental duplications are enriched with genes that are differentially expressed between humans and chimpanzees.
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ژورنال
عنوان ژورنال: Cell Reports
سال: 2020
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2020.108308